Visiting Scientists

To complement the network's capacity to transfer new knowledge and strengthen supervision, a limited number of visiting scientists (26 months altogether) originating from both the public and the private sector will be recruited to take part in the training research programme. These visiting scientists will be outstanding in international training and collaborative research. Visiting scientists will contribute to the international expertise of the network, participate and reinforce training courses, and provide contacts to PhD students with other international laboratories by helping them to prepare their future carrier and open their mind. The presence of visiting scientists from several industrial partners will allow for direct exchange with the PhD students, and will transfer the newest technological developments to characterize MPs and the pertinent medical and pharmaceutical questions on MPs. This will significantly support future engagement of students in the private sector.

Nb Visiting scientist Involvement in the training and research activities
1. Olivier SOUBIAS Participation to workshop(s): Structural and functional consequences of the interaction of polyunsaturated lipids with the GPCR rhodopsin. Knowledge exchange: Reconstitution of GPCRs in lipid membranes for functional studies / Recent advances in solid state NMR to study lipid-protein interaction and lipid dynamics.
2. Martial PIOTTO I will organize lectures on High Resolution Magic Angle Spinning (HRMAS) NMR spectroscopy which may have a high impact NMR of MPs.
3.
Alexander SPIRIN,
Vladimir SHIROKOV
High-yield expression of target proteins in eukaryotic (wheat germ) and bacterial (E. coli)continuous-exchange (dialysis) cell free expression systems. Design of mRNA constructs for high-yield expression in wheat germ system. Taking part in the workshops, short visits to partners's labs to give talks/seminars relative to the cell-free expression systems.
4. John BAENZIGER Prof Baenziger will contribute to workshops as required and will teach workshops on the application of FTIR to study integral membrane protein structure and function. In particular, he uses a novel FTIR method for monitoring residue-specific structural changes that occur upon ligand-binding to integral membrane receptors. He will collaborate with Dr. Eva Pebay-Peyroula.
5. Krzysztof PALCZEWSKI Prof. Palczewski agreed to take part in one or more of the workshops the consortium plans to organize on the biology of membrane proteins and high-resolution structure of membrane proteins. Dr. Palczewski plans to stay for a few weeks each time In the laboratories of D. Müller, A. Engel and G. Büldt and give a hand to the Ph.D. projects. Case Western Reserve University Department of Pharmacology will accept 4-5 students/year to advance the educational aspect and training opportunity, giving them access to all approaches and techniques and instrumentation available at the Medical School.
6. Thomas SCHMIDT T. Schmidt will join the Vogel group to apply his unique in vivo single-molecule microscopy expertise to imaging of olfactory receptor behavior on controlled chemical stimulation in structured u-channels joining the PhD-student working on this project. During this visit he will further give a lecture series on In Vivo Single-Molecule Microscopy open to PhD students and staff of the consortium.
7. D.M. ENGELMAN The Engelman Laboratory will participate in two ways: (1) D. Engelman will visit In Europe, initially at the I.B.P.C. in Paris, to present lectures over a two-to-three-week period and to hale discussions of ongoing science, and (2) the Engelman Laboratory will welcome short-term visits by members of the European groups for training in our methods and approaches.
8. Shinya YOSHIKAWA Prof. Yoshikawa works on the cytochrome oxidase, has a close profile with a dual experience in biochemistry and crystallisation of membrane proteins.
9. Melanie COCCO Lectures on solution state NMR techniques applied to membrane proteins; detergents and membrane mimetics; reconstitution of porins; peripherally associated membrane proteins.
10. Robert GRIFFIN Participation in one or more of the workshops we plan to organize on NMR of membrane proteins. I would also plan short stays in Marc Baldus’ and/or Hartmut Oschkinat’s lab to give talks and converse with students. We also have visitors from these groups for short visits to learn about dynamic nuclear polarization experiments.
11. BÜLDTG. Seminars, lectures as well as a practical course on application of the scattering techniques for membrane structural biology. Short visits to the labs involved in the projekt to share our theoretical and practical experience in membrane structural biology and help the students (including seminars and lectures). Short visits of one or more pupils to my lab and giving them access to some approaches we are currently developing
12.
L. YAGUZHINSKIY,
A. KUKLIN
Seminars, lectures on membrane biochemistry, help Ph.D. students in biochemistry of membrane proteins. Short visits to the labs involved in the project to share our theoretical and practical experience in membrane protein biochemistry and help the students (including seminars and lectures). Seminars and practical courses on SANS studies of membrane systems. Providing beam time at SANS instrument at FLNPh in Dubna for the needs of the project and helping students to carry out SANS studies. Short visits to the labs involved In the project to share experience in membrane structural biology via SANS and help the students (including seminars and lectures). Short visits of the students to FLNPh to carry out their SANS research on membrane proteins and systems.
13.
M. ENGELHARD,
J. KLARE
Seminars, lectures on molecular biology of membrane proteins. Short visits to our labs of one or more pupils and giving them access to some approaches we are currently developing (for instance, solid state NMR with microcrystals of membrane proteins (together with Dr. M. Baldus)). Short visits to the labs involved in the project to share our theoretical and practical experience in molecular biology of membrane proteins and help the students (including seminars and lectures).